Anticorps Recombinant de lapin anti-CD38

CD38 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG

Réactivité testée

Lapin

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241357C3

N° de cat : 84689-1-PBS

Synonymes

241357C3

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Galerie de données de validation

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  WB analysis of rabbit splenocytes using 84689-1-MR (same clone as 84689-1-PBS)

  rabbit splenocytes were subjected to SDS PAGE followed by western blot with 84689-1-MR (CD38 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84689-1-PBS in a different storage buffer formulation.

• 

  WB analysis of rabbit serum using 84689-1-MR (same clone as 84689-1-PBS)

  rabbit serum was subjected to SDS PAGE followed by western blot with 84689-1-MR (CD38 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84689-1-PBS in a different storage buffer formulation.

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Informations sur le produit

84689-1-PBS cible CD38 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Lapin

• Réactivité: Lapin
• Hôte / Isotype: Mouse / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: CD38
• Poids moléculaire observé: 45-50 kDa
• Symbole du gène: CD38
• Identification du gène (NCBI): 100009409
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CD38, also known as ADP-ribosyl cyclase 1, is a type II transmembrane glycoprotein with a short N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites (PMID: 2319135). The extracellular domain of CD38 has bifunctional enzyme activities that catalyze synthesis of cyclic ADP ribose from nicotinamide adenine dinucleotide (NAD) and hydrolysis of cyclic ADP ribose to adenosine diphosphoribose (PMID: 10636863). CD38 is expressed on a variety of hematopoietic and non-hematopoietic cells and is involved in diverse processes such as generation of calcium-mobilizing metabolites, cell activation, and chemotaxis (PMID: 25938500).

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