Anticorps Recombinant de lapin anti-CD38

CD38 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

250107D9

N° de cat : 85843-1-PBS

Synonymes

ADP ribosyl cyclase/cyclic ADP ribose hydrolase, CD38 antigen, Cyclic ADP ribose hydrolase 1

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Galerie de données de validation

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  WB analysis using 85843-1-RR (same clone as 85843-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85843-1-RR (Cd38 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85843-1-PBS in a different storage buffer formulation.

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Informations sur le produit

85843-1-PBS cible CD38 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons rat, souris

• Réactivité: rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CD38 Protéine recombinante Eg2915
• Nom complet: CD38 antigen
• Masse moléculaire calculée: 34 kDa
• Poids moléculaire observé: 40-45 kDa
• Numéro d’acquisition GenBank: NM_007646.5
• Symbole du gène: Cd38
• Identification du gène (NCBI): 12494
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CD38, also known as ADP-ribosyl cyclase 1, is a type II transmembrane glycoprotein with a short N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites (PMID: 2319135). The extracellular domain of CD38 has bifunctional enzyme activities that catalyze synthesis of cyclic ADP ribose from nicotinamide adenine dinucleotide (NAD) and hydrolysis of cyclic ADP ribose to adenosine diphosphoribose (PMID: 10636863). CD38 is expressed on a variety of hematopoietic and non-hematopoietic cells and is involved in diverse processes such as generation of calcium-mobilizing metabolites, cell activation, and chemotaxis (PMID: 25938500).

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