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Anticorps Recombinant de lapin anti-CD40L/CD154

CD40L/CD154 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242847A5

N° de cat : 85209-4-PBS

Synonymes

CD154, CD40L; CD154, CD40LG, CD40 ligand, CD40 L

Galerie de données de validation

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  • Western Blot (WB) analysis of human peripheral blood platelets using CD40L/CD154 Recombinant antibody (85209-4-RR)

    WB analysis of human peripheral blood platelets using 85209-4-RR (same clone as 85209-4-PBS)

    human peripheral blood platelets were subjected to SDS PAGE followed by western blot with 85209-4-RR (CD40L/CD154 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85209-4-PBS in a different storage buffer formulation.

Informations sur le produit

85209-4-PBS cible CD40L/CD154 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Recombinant
Type Anticorps
Immunogène Protéine recombinante
Nom complet CD40 ligand
Masse moléculaire calculée 261 aa, 29 kDa
Poids moléculaire observé30 kDa
Numéro d’acquisition GenBankBC071754
Symbole du gène CD40 Ligand
Identification du gène (NCBI) 959
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par protéine A
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The CD40 ligand (CD40L, TRAP, CD154), a member of the TNF superfamily of ligands, is expressed as either a 33 kDa transmembrane homologue or an 18 kDa soluble form (sCD154). CD40L is primarily expressed on activated CD4+ T cells and a small proportion of CD8+ T cells and platelets. It binds to CD40 on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. Recent studies have suggested that CD40/CD40L interactions regulate oxidative stress and affect various signaling pathways in both the immunological and the cardiovascular systems. The CD40/CD40L system is also involved in tumorigenesis.

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