Anticorps Recombinant de lapin anti-CD45

CD45 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

240356D1

N° de cat : 98035-1-PBS

Synonymes

Ptprc, 240356D1, EC:3.1.3.48, LCA, L-CA

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Galerie de données de validation

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  FC experiment of mouse splenocytes using 98035-1-RR (same clone as 98035-1-PBS)

  1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CD45 Rabbit Recombinant Antibody (98035-1-RR, Clone: 240356D1) (red) or 0.25 ug Isotype Control (blue), and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98035-1-PBS in a different storage buffer formulation.

• 

  FC experiment of mouse splenocytes using 98035-1-RR (same clone as 98035-1-PBS)

  1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CD45 Rabbit Recombinant Antibody (98035-1-RR, Clone: 240356D1) or 0.25 ug Isotype Control, and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98035-1-PBS in a different storage buffer formulation.

• 

  Affinity and Kinetic Characterization of 98035-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98035-1 against Mouse CD45 were performed. The affinity constant is 0.787 nM.

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Informations sur le produit

98035-1-PBS cible CD45 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CD45 Protéine recombinante Eg0845
• Nom complet: protein tyrosine phosphatase, receptor type, C
• Masse moléculaire calculée: 145 kDa
• Numéro d’acquisition GenBank: NM_001111316.2
• Symbole du gène: CD45
• Identification du gène (NCBI): 19264
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

CD45, also known as protein tyrosine phosphatase, receptor type C, is a type I transmembrane protein expressed on the surface of all haematopoietic cells with the exception of erythrocytes and platelets (PMID: 3489673; 28615666). CD45 is a pan-haematopoietic cell marker and has been shown to be essential for T- and B-cell activation and signalling (PMID: 9429890; 16378097).

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