Anticorps Polyclonal de lapin anti-CD47

CD47 Polyclonal Antibody for IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 20305-1-PBS

Synonymes

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Galerie de données de validation

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  IHC staining of human prostate cancer using 20305-1-AP (same clone as 20305-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 20305-1-AP (CD47 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20305-1-PBS in a different storage buffer formulation.

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  IHC staining of human prostate cancer using 20305-1-AP (same clone as 20305-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 20305-1-AP (CD47 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20305-1-PBS in a different storage buffer formulation.

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  IHC staining of human ovary tumor using 20305-1-AP (same clone as 20305-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary tumor tissue slide using 20305-1-AP (CD47 Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20305-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human ovary tumor using 20305-1-AP (same clone as 20305-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary tumor tissue slide using 20305-1-AP (CD47 Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20305-1-PBS in a different storage buffer formulation.

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Informations sur le produit

20305-1-PBS cible CD47 dans les applications de IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: CD47 Protéine recombinante Ag14132
• Nom complet: CD47 molecule
• Masse moléculaire calculée: 323 aa, 35 kDa
• Numéro d’acquisition GenBank: BC010016
• Symbole du gène: CD47
• Identification du gène (NCBI): 961
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CD47, also known as integrin-associated protein (IAP), is a member of the immunoglobulin superfamily containing a five-pass transmembrane attachment. CD47 is heavily glycosylated and widely expressed by hematopoietic and nonhematopoietic cells. CD47 interacts with several membrane integrins and also acts as a receptor for thrombospondin (THBS1). It is involved in a range of cellular processes, including apoptosis, proliferation, adhesion, and migration. CD47 also functions as a ligand for signal regulatory protein-α (SIRPα). Upon binding CD47, SIRPα initiates a signaling cascade that results in the inhibition of phagocytosis.

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