Anticorps Monoclonal anti-CD5

CD5 Monoclonal Antibody for IHC, IF-P, Indirect ELISA

Hôte / Isotype

Mouse / IgG2b

Réactivité testée

Humain

Applications

IHC, IF-P, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

4D12C10

N° de cat : 67278-1-PBS

Synonymes

4D12C10, CD5 molecule, LEU1, Lymphocyte antigen T1/Leu 1, Lymphocyte antigen T1/Leu-1

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Galerie de données de validation

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  IHC staining of human tonsillitis using 67278-1-Ig (same clone as 67278-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 67278-1-Ig (CD5 antibody) at dilution of 1:2000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67278-1-PBS in a different storage buffer formulation.

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  IHC staining of human tonsillitis using 67278-1-Ig (same clone as 67278-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 67278-1-Ig (CD5 antibody) at dilution of 1:2000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67278-1-PBS in a different storage buffer formulation.

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  IHC staining of human tonsillitis using 67278-1-Ig (same clone as 67278-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 67278-1-Ig (CD5 antibody) at dilution of 1:2000 (under 4x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67278-1-PBS in a different storage buffer formulation.

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  IF Staining of human tonsillitis using 67278-1-Ig (same clone as 67278-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed human tonsillitis tissue using CD5 antibody (67278-1-Ig, Clone: 4D12C10 ) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 67278-1-PBS in a different storage buffer formulation.

• 

  IF Staining of human tonsillitis using 67278-1-Ig (same clone as 67278-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed human tonsillitis tissue using CD5 antibody (67278-1-Ig, Clone: 4D12C10 ) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 67278-1-PBS in a different storage buffer formulation.

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Informations sur le produit

67278-1-PBS cible CD5 dans les applications de IHC, IF-P, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG2b
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: CD5 Protéine recombinante Ag11065
• Nom complet: CD5 molecule
• Masse moléculaire calculée: 495 aa, 55 kDa
• Numéro d’acquisition GenBank: BC027901
• Symbole du gène: CD5
• Identification du gène (NCBI): 921
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CD5 is a type I transmembrane glycoprotein of the scavenger receptor cysteine-rich family (PMID: 12403363). CD5 is expressed on a majority of thymocytes, mature T cells, B cell subsets, and peripheral blood dendritic cells (PMID: 9858516; 6156984; 10379049; 1384337). CD5 may act as a receptor in regulating T-cell proliferation. It functions as a negative regulator of TCR signaling during thymocyte development (PMID: 7542801).

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