Anticorps Recombinant de lapin anti-CD5

CD5 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

240428A12

N° de cat : 98054-1-PBS

Synonymes

T1, Lymphocyte antigen T1/Leu-1, Lymphocyte antigen T1/Leu 1, LEU1, CD5 molecule

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Galerie de données de validation

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  FC experiment of human PBMCs using 98054-1-RR (same clone as 98054-1-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD5 Rabbit Recombinant Antibody (98054-1-RR, Clone: 240428A12) or 0.25 ug Isotype Control, and PE-conjugated Goat Anti-Rabbit IgG. Cells were then stained with CoraLite® Plus 647 Anti-Human CD19. Cells were not fixed. Lymphocytes were gated. This data was developed using the same antibody clone with 98054-1-PBS in a different storage buffer formulation.

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  FC experiment of human PBMCs using 98054-1-RR (same clone as 98054-1-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD5 Rabbit Recombinant Antibody (98054-1-RR, Clone: 240428A12) (red) or 0.25 ug Isotype Control (blue), and PE-conjugated Goat Anti-Rabbit IgG. Cells were not fixed. Lymphocytes were gated. This data was developed using the same antibody clone with 98054-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 98054-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98054-1-RR against Human CD5 were performed. The affinity constant is 0.27 nM.

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Informations sur le produit

98054-1-PBS cible CD5 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: CD5 molecule
• Masse moléculaire calculée: 55 kDa
• Numéro d’acquisition GenBank: NM_014207.4
• Symbole du gène: CD5
• Identification du gène (NCBI): 921
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

CD5 is a type I transmembrane glycoprotein of the scavenger receptor cysteine-rich family (PMID: 12403363). CD5 is expressed on a majority of thymocytes, mature T cells, B cell subsets, and peripheral blood dendritic cells (PMID: 9858516; 6156984; 10379049; 1384337). CD5 may act as a receptor in regulating T-cell proliferation. It functions as a negative regulator of TCR signaling during thymocyte development (PMID: 7542801).

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