Anticorps Recombinant de lapin anti-CD55

CD55 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

250682C11

N° de cat : 98493-3-PBS

Synonymes

Complement decay-accelerating factor, CR, CROM, DAF, TC

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Galerie de données de validation

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  FC experiment of human blood using 98493-3-RR (same clone as 98493-3-PBS)

  1x10^6 human blood cells were surface stained with 0.25 ug Anti-Human CD55 Rabbit RecAb (98493-3-RR, Clone: 250682C11) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-conjugated Goat Anti-Rabbit IgG. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98493-3-PBS in a different storage buffer formulation.

• 

  FC experiment of human blood using 98493-3-RR (same clone as 98493-3-PBS)

  1x10^6 human blood cells were surface stained with 0.25 ug Anti-Human CD55 Rabbit RecAb (98493-3-RR, Clone:250682C11) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-conjugated Goat Anti-Rabbit IgG. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98493-3-PBS in a different storage buffer formulation.

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Informations sur le produit

98493-3-PBS cible CD55 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CD55 Protéine recombinante Eg4246
• Nom complet: CD55 molecule, decay accelerating factor for complement (Cromer blood group)
• Masse moléculaire calculée: 41 kDa
• Numéro d’acquisition GenBank: BC001288
• Symbole du gène: CD55
• Identification du gène (NCBI): 1604
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

CD55, also known as DAF, is a glycosylphosphatidylinositol (GPI)-anchored surface glycoprotein that is widely distributed on blood, stroma, epithelial, and endothelial cells (PMID: 7517044; 29503741). It can also exist as a soluble form in plasma, urine, saliva, tears, and synovial fluids (PMID: 29503741). CD55 is a complement regulatory protein (PMID: 2469439; 7517044). It inhibits formation of the C3 convertases through binding to C3b and C4b. It also binds the alternate pathway convertase C3bBb, the classical pathway convertase and C4b2a to accelerate their decay (PMID: 17289551). CD55 also serves as a receptor for coxsackieviruses B1, B3, and B5 and several enteroviruses (PMID: 7538177; 7517044).

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