Anticorps Recombinant de lapin anti-CD55

CD55 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

CoraLite®594 Fluorescent Dye

CloneNo.

241808D11

N° de cat : CL594-98228

Synonymes

241808D11, Cd55a, Complement decay-accelerating factor, GPI-anchored, Daf, Daf1

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Galerie de données de validation

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  FC experiment of mouse splenocytes using CL594-98228

  1x10^6 mouse splenocytes were surface stained with APC Anti-Mouse CD45R (B220) (RA3-6B2) (APC-65139, Clone: RA3-6B2), and 0.25 ug CoraLite®594 Anti-Mouse CD55 Rabbit RecAb (CL594-98228, Clone: 241808D11) or CoraLite®594 Rabbit IgG Isotype Control RecAb (CL594-98136, Clone: 240953C9). Cells were not fixed.

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  FC experiment of mouse splenocytes using CL594-98228

  1x10^6 mouse splenocytes were surface stained with 0.25 ug CoraLite®594 Anti-Mouse CD55 Rabbit RecAb (CL594-98228, Clone: 241808D11) (red) or CoraLite®594 Rabbit IgG Isotype Control RecAb (CL594-98136, Clone: 240953C9) (blue). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: splénocytes de souris,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

CL594-98228 cible CD55 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CD55 Protéine recombinante Eg2124
• Nom complet: CD55 antigen
• Masse moléculaire calculée: 43kDa
• Numéro d’acquisition GenBank: NM_010016.3
• Symbole du gène: CD55
• Identification du gène (NCBI): 13136
• Conjugaison: CoraLite®594 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 588 nm / 604 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

CD55, also known as DAF, is a glycosylphosphatidylinositol (GPI)-anchored surface glycoprotein that is widely distributed on blood, stroma, epithelial, and endothelial cells (PMID: 7517044; 29503741). It can also exist as a soluble form in plasma, urine, saliva, tears, and synovial fluids (PMID: 29503741). CD55 is a complement regulatory protein (PMID: 2469439; 7517044). It inhibits formation of the C3 convertases through binding to C3b and C4b. It also binds the alternate pathway convertase C3bBb, the classical pathway convertase and C4b2a to accelerate their decay (PMID: 17289551). CD55 also serves as a receptor for coxsackieviruses B1, B3, and B5 and several enteroviruses (PMID: 7538177; 7517044).

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