Anticorps Recombinant de lapin anti-NCAM1/CD56

NCAM1/CD56 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

240936A4

N° de cat : 98118-1-PBS

Synonymes

Ncam1, CD56, 240936A4, NCAM 1, Ncam

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Galerie de données de validation

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  FC experiment of mouse bone marrow cells using 98118-1-RR (same clone as 98118-1-PBS)

  1x10^6 mouse bone marrow cells were surface stained with 0.25 ug Anti-Mouse CD56 Rabbit Recombinant Antibody (98118-1-RR, Clone: 240936A4) or 0.25 ug Isotype Control, and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98118-1-PBS in a different storage buffer formulation.

• 

  FC experiment of mouse bone marrow cells using 98118-1-RR (same clone as 98118-1-PBS)

  1x10^6 mouse bone marrow cells were surface stained with 0.25 ug Anti-Mouse CD56 Rabbit Recombinant Antibody (98118-1-RR, Clone:240936A4) (red) or 0.25 ug Isotype Control (blue), and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98118-1-PBS in a different storage buffer formulation.

• 

  Affinity and Kinetic Characterization of 98118-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98118-1-RR against Mouse CD56 were performed. The affinity constant is 9.50 nM.

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Informations sur le produit

98118-1-PBS cible NCAM1/CD56 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: neural cell adhesion molecule 1
• Masse moléculaire calculée: 119 kDa
• Symbole du gène: Ncam1
• Identification du gène (NCBI): 17967
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

Neural cell adhesion molecule 1 (NCAM1, also known as CD56, NCAM, and MSK39) is a membrane-bound cell surface glycoprotein and a member of the immunoglobulin supergene family, which induces cell-to-cell interactions during embryonic development, cell migration, and organogenesis (PMID: 8013635; 1855476; 1391354). Mouse natural killer (NK) cells do not express the murine homolog of CD56 (PMID: 17100875). The molecular weight of NCAM1 changes from the 120 kDa isoform in normal tissue to the 140/180 kDa isoforms in tumors (PMID: 10086383).

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