Anticorps Recombinant de lapin anti-CD6

CD6 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

FITC Plus Fluorescent Dye

CloneNo.

241965C9

N° de cat : FITC-98223

Synonymes

241965C9, CD6 molecule, Soluble CD6, T12, T-cell differentiation antigen CD6

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Galerie de données de validation

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  FC experiment of human PBMCs using FITC-98223

  1x10^6 human PBMCs were surface stained with APC Anti-Human CD3, and 5 ul FITC Plus Anti-Human CD6 Rabbit RecAb (FITC-98223, Clone: 241965C9) or FITC Plus Rabbit IgG Isotype Control RecAb (FITC-98136, Clone: 240953C9). Cells were not fixed. Lymphocytes were gated.

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  FC experiment of human PBMCs using FITC-98223

  1x10^6 human PBMCs were surface stained with 5 ul FITC Plus Anti-Human CD6 Rabbit RecAb (FITC-98223, Clone: 241965C9) (red) or FITC Plus Rabbit IgG Isotype Control RecAb (FITC-98136, Clone: 240953C9) (blue). Cells were not fixed. Lymphocytes were gated.

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Applications testées

• Résultats positifs en cytométrie: CMSP humaines,

Dilution recommandée

Application	Dilution
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Informations sur le produit

FITC-98223 cible CD6 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CD6 Protéine recombinante Eg2079
• Nom complet: CD6 molecule
• Numéro d’acquisition GenBank: BC033755
• Symbole du gène: CD6
• Identification du gène (NCBI): 923
• Conjugaison: FITC Plus Fluorescent Dye
• Excitation/Emission maxima wavelengths: 495 nm / 524 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide and 0.5% BSA
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

CD6 is a type I transmembrane glycoprotein that belongs to the scavenger receptor cysteine-rich superfamily (PMID: 21880988). It is composed of an extracellular region, which consists of three tandem SRCR domains, a transmembrane region, and a cytoplasmic tail devoid of intrinsic catalytic activity but harboring several phosphorylatable residues suitable for intracellular signal transduction (PMID: 38139340; 23711376). CD6 is expressed by T cells, medullary thymocytes, a subset of B cells and NK cells, and in some cells of the brain (PMID: 1919444; 21178331). CD6 plays a role in lymphocyte activation, proliferation, and survival processes via interaction with its endogenous ligands.

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