Anticorps Recombinant de lapin anti-CD62P

CD62P Recombinant Antibody for FC

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain

Applications

FC

Conjugaison

PE Fluorescent Dye

CloneNo.

AK4

N° de cat : PE-65587

Synonymes

P-selectin, GMRP, GMP-140, GMP140, GMP 140

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Galerie de données de validation

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  FC experiment of human peripheral blood platelets using PE-65587

  1x10^6 thrombin treated human peripheral blood platelets were surface stained with 5 ul PE Anti-Human CD62P (AK4) Mouse IgG2a Recombinant Antibody (PE-65587, Clone: AK4) (red), or PE Mouse IgG2a Isotype Control (C1.18.4) (PE-65208, Clone: C1.18.4) (blue). 1x10^6 untreated human peripheral blood platelets were surface stained with 5 ul PE Anti-Human CD62P (AK4) Mouse IgG2a Recombinant Antibody (PE-65587, Clone: AK4) (black). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: Thrombin treated human peripheral blood platelets,

Dilution recommandée

Application	Dilution
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Informations sur le produit

PE-65587 cible CD62P dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Plaquettes humaines
• Nom complet: selectin P (granule membrane protein 140kDa, antigen CD62)
• Masse moléculaire calculée: 830 aa, 91 kDa
• Numéro d’acquisition GenBank: BC028067
• Symbole du gène: CD62P
• Identification du gène (NCBI): 6403
• Conjugaison: PE Fluorescent Dye
• Excitation/Emission maxima wavelengths: 496 nm, 565 nm / 578 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide and 0.5% BSA
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

P-selectin, also known as GMP140 or CD62P, is a transmembrane glycoprotein that mediates the interaction of activated endothelial cells or platelets with leukocytes. It is an adhesion molecule involved in the pathogenesis of inflammation, thrombosis, and oncogenesis. P-selectin is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.

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