Anticorps Recombinant de lapin anti-CD63

CD63 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

CoraLite® Plus 647 Fluorescent Dye

CloneNo.

241964E1

N° de cat : CL647-98318

Synonymes

241964E1, CD 63, CD63 antigen, Limp1, Lysosomal-associated membrane protein 3

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Galerie de données de validation

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  FC experiment of human peripheral blood platelets using CL647-98318

  1x10^6 thrombin-treated human peripheral blood platelets were surface stained with 5 ul CoraLite® Plus 647 Anti-Human CD63 Rabbit RecAb (CL647-98318, Clone: 241964E1) (red) or CoraLite® Plus 647 Rabbit IgG Isotype Control RecAb (CL647-98136, Clone: 240953C9) (blue). 1x10^6 untreated human peripheral blood platelets were surface stained with 5 ul CoraLite® Plus 647 Anti-Human CD63 Rabbit RecAb (CL647-98318, Clone: 241964E1) (black, dashed). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: Thrombin treated human peripheral blood platelets,

Dilution recommandée

Application	Dilution
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Informations sur le produit

CL647-98318 cible CD63 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CD63 Protéine recombinante Eg2064
• Nom complet: CD63 molecule
• Masse moléculaire calculée: 26 kDa
• Numéro d’acquisition GenBank: BC002349
• Symbole du gène: CD63
• Identification du gène (NCBI): 967
• Conjugaison: CoraLite® Plus 647 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 654 nm / 674 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide and 0.5% BSA
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

CD63 is a 30-60 kDa lysosomal membrane protein that belongs to the tetraspanin family. This protein plays many important roles in immuno-physiological functions. It mediates signal transduction events that regulate cell development, activation, growth, and motility. CD63 is expressed on activated platelets, thus it may function as a blood platelet activation marker. CD63 is a lysosomal membrane glycoprotein translocated to the plasma membrane after platelet activation. The CD63 tetraspanin is highly expressed in the early stages of melanoma and decreases in advanced lesions, suggesting it is a possible suppressor of tumor progression. Deficiency of this protein is associated with Hermansky-Pudlak syndrome.

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