Anticorps Recombinant de lapin anti-CD64

CD64 Recombinant Antibody for FC

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain

Applications

FC

Conjugaison

Biotin

CloneNo.

10.1

N° de cat : Biotin-65572

Synonymes

Fc-gamma RI, FCG1, Fc gamma RIA, Fc gamma RI, CD64A

---

Galerie de données de validation

• 

  FC experiment of human PBMCs using Biotin-65572

  1x10^6 human PBMCs were surface stained with 0.25 ug Biotin Anti-Human CD64 (10.1) Mouse IgG2a RecAb (Biotin-65572, Clone:10.1) and CoraLite®488-conjugated streptavidin, or unstained. Cells were co-stained with APC Anti-Human CD14 Rabbit Recombinant Antibody (APC-98040, Clone: 230332D7). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

• 

  FC experiment of human PBMCs using Biotin-65572

  1x10^6 human PBMCs were surface stained with 0.25 ug Biotin Anti-Human CD64 (10.1) Mouse IgG2a RecAb (Biotin-65572, Clone:10.1) and CoraLite®488-conjugated streptavidin (red) or unstained (blue).Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

---

Applications testées

• Résultats positifs en cytométrie: CMSP humaines

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

Biotin-65572 cible CD64 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Human rheumatoid synovial fluid cells and fibronectin-purified monocytes.
• Nom complet: Fc fragment of IgG, high affinity Ia, receptor (CD64)
• Masse moléculaire calculée: 374 aa, 43 kDa
• Numéro d’acquisition GenBank: BC032634
• Symbole du gène: FCGR1A
• Identification du gène (NCBI): 2209
• Conjugaison: Biotin
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

Fcγ receptor comprise a multigene family of integral membrane glycoproteins that exhibit complex activation or inhibitory effects on cell functions after aggregation by complexed immunoglobulin G (IgG) (PMID: 17005690 ). CD64, also known as FcγRIA, is a high-affinity receptor for the Fc region of IgG. It is expressed by monocytes/macrophages, activated neutrophils, dendritic cells, and early myeloid cells (PMID: 23293080; 19642859; 7680917). CD64 functions in both innate and adaptive immune responses.

{{ptg:RelatedPrimaryAntibodies}}