Anticorps Monoclonal anti-CD7
CD7 Monoclonal Antibody for FC
Hôte / Isotype
Mouse / IgG2a, kappa
Réactivité testée
Humain
Applications
FC
Conjugaison
Non conjugué
CloneNo.
4H9
N° de cat : 65203-1-Ig
Synonymes
Galerie de données de validation
Applications testées
| Résultats positifs en cytométrie | CMSP humaines, | 
Dilution recommandée
| Application | Dilution | 
|---|---|
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, check data in validation data gallery | |
Informations sur le produit
65203-1-Ig cible CD7 dans les applications de FC et montre une réactivité avec des échantillons Humain
| Réactivité | Humain | 
| Hôte / Isotype | Mouse / IgG2a, kappa | 
| Clonalité | Monoclonal | 
| Type | Anticorps | 
| Immunogène | Cellules de leucémie lymphoblastique aiguë T | 
| Nom complet | CD7 molecule | 
| Masse moléculaire calculée | 240 aa, 25 kDa | 
| Numéro d’acquisition GenBank | BC009293 | 
| Symbole du gène | CD7 | 
| Identification du gène (NCBI) | 924 | 
| Conjugaison | Non conjugué | 
| Forme | Liquide | 
| Méthode de purification | Purification par protéine A | 
| Tampon de stockage | PBS with 0.09% sodium azide | 
| Conditions de stockage | Store at 2-8°C. Stable for one year after shipment. | 
Informations générales
CD7, also known as Leu-9 or GP40, is a 40-kDa single-pass type I transmembrane glycoprotein belonging to the immunoglobulin superfamily. CD7 is expressed on thymocytes, T cells, NK cells, and cells in the early stages of T, B, and myeloid cell differentiation (PMID: 10530432). It is one of the earliest antigens to appear on cells of the T-lymphocyte lineage (PMID: 3501369). CD7 plays a significant role in T-cell and T-cell/B-cell interactions during early lymphoid development. It is involved in the regulation of cell signaling and biology, including T-cell activation, proliferation, and the expression of interleukin-2 receptor alpha (IL-2Rα) (PMID: 11485208). CD7 is not only a marker for T-cells but also has functional implications in immune cell interactions and adhesion. It can provide co-stimulatory signals and is associated with CD3 and CD45, participating in T-cell activation (PMID: 7523512).
Protocole
| Product Specific Protocols | |
|---|---|
| FC protocol for CD7 antibody 65203-1-Ig | Download protocol | 
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols | 

