Anticorps Recombinant de lapin anti-CD7

CD7 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

242402H8

N° de cat : 98204-1-PBS

Synonymes

242402H8, CD7 molecule, GP40, LEU-9, T cell antigen CD7

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Galerie de données de validation

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  FC experiment of human PBMCs using 98204-1-RR (same clone as 98204-1-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD7 Rabbit Recombinant Antibody (98204-1-RR, Clone: 242402H8) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with APC Anti-Human CD4. Cells were not fixed. Lymphocytes were gated. This data was developed using the same antibody clone with 98204-1-PBS in a different storage buffer formulation.

• 

  FC experiment of human PBMCs using 98204-1-RR (same clone as 98204-1-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD7 Rabbit Recombinant Antibody (98204-1-RR, Clone: 242402H8) (red) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98204-1-PBS in a different storage buffer formulation.

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Informations sur le produit

98204-1-PBS cible CD7 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CD7 Protéine recombinante Eg3034
• Nom complet: CD7 molecule
• Masse moléculaire calculée: 25 kDa
• Numéro d’acquisition GenBank: NM_006137.7
• Symbole du gène: CD7
• Identification du gène (NCBI): 924
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

CD7, also known as Leu-9 or GP40, is a 40-kDa single-pass type I transmembrane glycoprotein belonging to the immunoglobulin superfamily. CD7 is expressed on thymocytes, T cells, NK cells, and cells in the early stages of T, B, and myeloid cell differentiation (PMID: 10530432). It is one of the earliest antigens to appear on cells of the T-lymphocyte lineage (PMID: 3501369). CD7 plays a significant role in T-cell and T-cell/B-cell interactions during early lymphoid development. It is involved in the regulation of cell signaling and biology, including T-cell activation, proliferation, and the expression of interleukin-2 receptor alpha (IL-2Rα) (PMID: 11485208). CD7 is not only a marker for T-cells but also has functional implications in immune cell interactions and adhesion. It can provide co-stimulatory signals and is associated with CD3 and CD45, participating in T-cell activation (PMID: 7523512).

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