Anticorps Recombinant de lapin anti-CD7

CD7 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Biotin

CloneNo.

242402H8

N° de cat : Biotin-98204

Synonymes

242402H8, CD7 molecule, GP40, LEU-9, T cell antigen CD7

---

Galerie de données de validation

• 

  FC experiment of human PBMCs using Biotin-98204

  1x10^6 human PBMCs were surface stained with 0.25 ug Biotin Anti-Human CD7 Rabbit RecAb (Biotin-98204, Clone: 242402H8) and CoraLite®488-conjugated streptavidin, or unstained. Cells were co-stained with APC Anti-Human CD4 (RPA-T4) (APC-65143, Clone: RPA-T4). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

• 

  FC experiment of human PBMCs using Biotin-98204

  1x10^6 human PBMCs were surface stained with 0.25 ug Biotin Anti-Human CD7 Rabbit RecAb (Biotin-98204, Clone: 242402H8) and CoraLite®488-conjugated streptavidin (red), or unstained (blue). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

---

Applications testées

• Résultats positifs en cytométrie: CMSP humaines

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

Biotin-98204 cible CD7 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CD7 Protéine recombinante Eg3034
• Nom complet: CD7 molecule
• Masse moléculaire calculée: 25 kDa
• Numéro d’acquisition GenBank: NM_006137.7
• Symbole du gène: CD7
• Identification du gène (NCBI): 924
• Conjugaison: Biotin
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

CD7, also known as Leu-9 or GP40, is a 40-kDa single-pass type I transmembrane glycoprotein belonging to the immunoglobulin superfamily. CD7 is expressed on thymocytes, T cells, NK cells, and cells in the early stages of T, B, and myeloid cell differentiation (PMID: 10530432). It is one of the earliest antigens to appear on cells of the T-lymphocyte lineage (PMID: 3501369). CD7 plays a significant role in T-cell and T-cell/B-cell interactions during early lymphoid development. It is involved in the regulation of cell signaling and biology, including T-cell activation, proliferation, and the expression of interleukin-2 receptor alpha (IL-2Rα) (PMID: 11485208). CD7 is not only a marker for T-cells but also has functional implications in immune cell interactions and adhesion. It can provide co-stimulatory signals and is associated with CD3 and CD45, participating in T-cell activation (PMID: 7523512).

{{ptg:RelatedPrimaryAntibodies}}