Anticorps Recombinant de lapin anti-CD71

CD71 Recombinant Antibody for FC

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

OKT9

N° de cat : 65605-1-PBS

Synonymes

TFR1, TFR, T9, sTfR, p90

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Galerie de données de validation

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  FC experiment of human PBMCs using 65605-1-MR (same clone as 65605-1-PBS)

  1x10^6 PHA treated human PBMCs were surface stained with 0.25 ug Anti-Human CD71 Mouse IgG2a Recombinant Antibody (65605-1-MR, Clone: OKT9) (red) or Mouse IgG2a Isotype Control (65208-1-Ig, Clone: C1.18.4) (blue) and CoraLite®488-Conjugated AffiniPure Donkey Anti-Mouse IgG(H+L). Untreated human PBMCs were surface stained with 0.25 ug Anti-Human CD71 Mouse IgG2a Recombinant Antibody (65605-1-MR, Clone: OKT9) and CoraLite®488-Conjugated AffiniPure Donkey Anti-Mouse IgG(H+L) (black). Cells were not fixed. This data was developed using the same antibody clone with 65605-1-PBS in a different storage buffer formulation.

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Informations sur le produit

65605-1-PBS cible CD71 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Human T-cell acute lymphoblastic leukemia cells
• Nom complet: transferrin receptor (p90, CD71)
• Masse moléculaire calculée: 85 kDa
• Numéro d’acquisition GenBank: BC001188
• Symbole du gène: CD71
• Identification du gène (NCBI): 7037
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

CD71, also known as transferrin receptor protein 1 (TfR1), is a transmembrane glycoprotein composed of two disulfide-linked monomers, each of 90 kDa molecular weight. Each monomer binds one holo-transferrin molecule creating an iron-Tf-TfR complex that enters the cell by endocytosis. CD71 is present on actively proliferating cells and is essential for iron transport into proliferating cells.

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