Anticorps Recombinant de lapin anti-CD73

CD73 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

CoraLite®594 Fluorescent Dye

CloneNo.

241541G9

N° de cat : CL594-98199

Synonymes

241541G9, 5'-deoxynucleotidase, 5'-NT, 5'-nucleotidase, EC:3.1.3.99

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Galerie de données de validation

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  FC experiment of mouse splenocytes using CL594-98199

  1x10^6 mouse splenocytes were surface stained with APC Anti-Mouse CD3, and 0.25 ug CoraLite®594 Anti-Mouse CD73 Rabbit RecAb (CL594-98199, Clone:241541G9) or CoraLite®594 Rabbit IgG Isotype Control RecAb (CL594-98136, Clone: 240953C9). Cells were not fixed.

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  FC experiment of mouse splenocytes using CL594-98199

  1x10^6 mouse splenocytes were surface stained with 0.25 ug CoraLite®594 Anti-Mouse CD73 Rabbit RecAb (CL594-98199, Clone: 241541G9) (red), and CoraLite®594 Rabbit IgG Isotype Control RecAb (CL594-98136, Clone: 240953C9) (blue). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: splénocytes de souris,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

CL594-98199 cible CD73 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CD73 Protéine recombinante Eg1389
• Nom complet: 5' nucleotidase, ecto
• Masse moléculaire calculée: 64kDa
• Numéro d’acquisition GenBank: NM_011851.4
• Symbole du gène: Nt5e
• Identification du gène (NCBI): 23959
• Conjugaison: CoraLite®594 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 588 nm / 604 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

CD73 is a membrane-bound enzyme that catalyzes the extracellular hydrolysis of adenosine monophosphate (AMP) to produce adenosine. It is expressed on various immune cells, including T cells, B cells, dendritic cells, and regulatory T cells (Tregs). CD73 works in conjunction with CD39 to break down extracellular ATP into adenosine, creating an immunosuppressive environment that can inhibit the function of cytotoxic T cells and natural killer (NK) cells. This process is essential for immune tolerance and the resolution of inflammation. CD73 is also an important player in controlling tumor progression.

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