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Anticorps Recombinant de lapin anti-CD74

CD74 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

250520B12

N° de cat : 86023-5-PBS

Synonymes

Class-II-associated invariant chain peptide, DHLAG, HLADG, HLA-DR antigens-associated invariant chain, Ia antigen-associated invariant chain

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using CD74 Recombinant antibody (86023-5-RR)

    WB analysis using 86023-5-RR (same clone as 86023-5-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86023-5-RR (CD74 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86023-5-PBS in a different storage buffer formulation.

Informations sur le produit

86023-5-PBS cible CD74 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Recombinant
Type Anticorps
Immunogène CD74 Protéine recombinante Eg1945
Nom complet CD74 molecule, major histocompatibility complex, class II invariant chain
Masse moléculaire calculée26 kDa
Poids moléculaire observé 37 kDa
Numéro d’acquisition GenBankNM_001025159.3
Symbole du gène CD74
Identification du gène (NCBI) 972
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par protéine A
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CD74, also known as MHC class II invariant chain Ii or HLA-DR-associated invariant chain, is a non-polymorphic type II transmembrane glycoprotein. CD74 is mainly distributed in B cells, monocytes, Langerhans cells, dendritic cells and thymic epithelial cells, and is also expressed in epithelial cells. CD74 plays a key role in MHC class II antigen processing and also serves as a cell surface receptor for the macrophage cytokine MIF. CD74 plays an important role in cardiovascular diseases such as atherosclerosis, ischemic heart disease, and myocardial hypertrophy.(PMID: 15475450; PMID: 27752708; PMID: 38992165; PMID: 36712241).

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