Anticorps Recombinant de lapin anti-CD74

CD74 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

250109G4

N° de cat : 98425-3-RR

Synonymes

Class-II-associated invariant chain peptide, CLIP, H-2 class II histocompatibility antigen gamma chain, Ia antigen-associated invariant chain, Ii

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Galerie de données de validation

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  FC experiment of mouse splenocytes using 98425-3-RR

  1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CD74 Rabbit RecAb (98425-3-RR, Clone: 250109G4) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with CoraLite® Plus 647 Anti-Mouse CD19 (1D3) (CL647-65290, Clone: 1D3). Cells were not fixed.

• 

  FC experiment of mouse splenocytes using 98425-3-RR

  1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CD74 Rabbit RecAb (98425-3-RR, Clone:250109G4) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: splénocytes de souris,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

98425-3-RR cible CD74 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CD74 Protéine recombinante Eg2716
• Nom complet: CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
• Masse moléculaire calculée: 32 kDa
• Numéro d’acquisition GenBank: NM_001042605.1
• Symbole du gène: Cd74
• Identification du gène (NCBI): 16149
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2 - 8°C. Stable for one year after shipment.

Informations générales

CD74, also known as MHC class II invariant chain Ii or HLA-DR-associated invariant chain, is a non-polymorphic type II transmembrane glycoprotein. CD74 is mainly distributed in B cells, monocytes, Langerhans cells, dendritic cells and thymic epithelial cells, and is also expressed in epithelial cells. CD74 plays a key role in MHC class II antigen processing and also serves as a cell surface receptor for the macrophage cytokine MIF. CD74 plays an important role in cardiovascular diseases such as atherosclerosis, ischemic heart disease, and myocardial hypertrophy.(PMID: 15475450; PMID: 27752708; PMID: 38992165; PMID: 36712241).

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