Anticorps Recombinant de lapin anti-CD79b

CD79b Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

241273B7

N° de cat : 98075-1-RR

Synonymes

IGB, Ig beta, B-cell-specific glycoprotein B29, B-cell antigen receptor complex-associated protein beta chain, B29

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Galerie de données de validation

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  FC experiment of human PBMCs using 98075-1-RR

  1x10^6 human PBMCs were stained with CoraLite® Plus 647 Anti-Human CD19 (4G7) Mouse IgG2a Recombinant Antibody (CL647-65562, Clone: 4G7) and 0.25 ug Anti-Human CD79b Rabbit Recombinant Antibody (98075-1-RR, Clone:241273B7), or Isotype Control. Cells were not fixed.

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  FC experiment of human PBMCs using 98075-1-RR

  1x10^6 human PBMCs were stained with 0.25 ug Anti-Human CD79b Rabbit Recombinant Antibody (98075-1-RR, Clone:241273B7) (red), or Isotype Control(blue). Cells were not fixed.

• 

  FC experiment of human PBMCs using 98075-1-RR

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD79b Rabbit Recombinant Antibody (98075-1-RR, Clone:241273B7) and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L), and 0.25 ug CoraLite® Plus 647 Anti-Human CD19 (4G7) Mouse IgG2a Recombinant Antibody (CL647-65562, Clone: 4G7), and 0.25 ug Isotype Control. Cells were not fixed.

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  Affinity and Kinetic Characterization of 98075-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98075-1-RR against Human CD79b were performed. The affinity constant is 1.41 nM.

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Applications testées

• Résultats positifs en cytométrie: CMSP humaines,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

98075-1-RR cible CD79b dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: CD79b molecule, immunoglobulin-associated beta
• Masse moléculaire calculée: 229 aa, 26 kDa
• Numéro d’acquisition GenBank: BC032651
• Symbole du gène: CD79B
• Identification du gène (NCBI): 974
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2 - 8°C. Stable for one year after shipment.

Informations générales

CD79 molecule encompasses two transmembrane proteins, CD79a and CD79b, which form a disulfide-linked heterodimer and are members of the immunoglobulin (Ig) gene superfamily (PMID: 2033258; 1375264; 2304550). CD79b molecule (also known as B29, IGB, AGM6, and Igbeta) is expressed almost exclusively on B cells and B-cell neoplasms, influencing antigen internalization and increasing antigen presentation efficiency (PMID: 7552998). CD79b mutation could be a key biomarker for DLBCL disease progression (PMID: 36182550).

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