Anticorps Recombinant de lapin anti-CD79b

CD79b Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

CoraLite® Plus 647 Fluorescent Dye

CloneNo.

241850D10

N° de cat : CL647-98217

Synonymes

241850D10, B-cell antigen receptor complex-associated protein beta chain, B-cell-specific glycoprotein B29, Igb, Ig-beta

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Galerie de données de validation

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  FC experiment of mouse bone marrow cells using CL647-98217

  1x10^6 mouse bone marrow cells were stained with CoraLite® Plus 488 Anti-Mouse CD45R (B220) (RA3-6B2) (CL488-65139, Clone: RA3-6B2), and 0.25 ug CoraLite® Plus 647 Anti-Mouse CD79b Rabbit RecAb (CL647-98217, Clone:241850D10) or CoraLite® Plus 647 Rabbit IgG Isotype Control RecAb (CL647-98136, Clone: 240953C9). Cells were not fixed.

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  FC experiment of mouse bone marrow cells using CL647-98217

  1x10^6 mouse bone marrow cells were stained with 0.25 ug CoraLite® Plus 647 Anti-Mouse CD79b Rabbit RecAb (CL647-98217, Clone: 241850D10)(red) or CoraLite® Plus 647 Rabbit IgG Isotype Control RecAb (CL647-98136, Clone: 240953C9) (blue). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: cellules médullaires de souris,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

CL647-98217 cible CD79b dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: CD79B antigen
• Masse moléculaire calculée: 26 kDa
• Numéro d’acquisition GenBank: NM_008339.3
• Symbole du gène: Cd79b
• Identification du gène (NCBI): 15985
• Conjugaison: CoraLite® Plus 647 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 654 nm / 674 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

CD79 molecule encompasses two transmembrane proteins, CD79a and CD79b, which form a disulfide-linked heterodimer and are members of the immunoglobulin (Ig) gene superfamily (PMID: 2033258; 1375264; 2304550). CD79b molecule (also known as B29, IGB, AGM6, and Igbeta) is expressed almost exclusively on B cells and B-cell neoplasms, influencing antigen internalization and increasing antigen presentation efficiency (PMID: 7552998). CD79b mutation could be a key biomarker for DLBCL disease progression (PMID: 36182550).

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