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Anticorps Recombinant de lapin anti-CD80

CD80 Recombinant Antibody for IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242913H3

N° de cat : 83198-4-PBS

Synonymes

B7-1, B7 1, B7, Activation B7-1 antigen, Activation B7 1 antigen

Galerie de données de validation

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  • Immunofluorescence (IF) / fluorescent staining of Raji cells using CD80 Recombinant antibody (83198-4-RR)

    IF Staining of Raji using 83198-4-RR (same clone as 83198-4-PBS)

    Immunofluorescent analysis of (4% PFA) fixed Raji cells using CD80 antibody (83198-4-RR, Clone: 242913H3 ) at dilution of 1:500 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 83198-4-PBS in a different storage buffer formulation.

Informations sur le produit

83198-4-PBS cible CD80 dans les applications de IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Recombinant
Type Anticorps
Immunogène Protéine recombinante
Nom complet CD80 molecule
Masse moléculaire calculée33 kDa
Numéro d’acquisition GenBankNM_005191
Symbole du gène CD80
Identification du gène (NCBI) 941
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par protéine A
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CD80 (also known as B7-1) is a type I membrane protein that is a member of the immunoglobulin superfamily, with an extracellular immunoglobulin constant-like domain and a variable-like domain required for receptor binding. It is expressed on antigen-presenting cells (APCs), including B cells, dendritic cells, monocytes, and macrophages. CD80 is the receptor for the proteins CD28 and CTLA-4 found on the surface of T-cells. It is involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. CD80 also acts as a cellular attachment receptor for adenovirus subgroup B. (PMID: 7545666; 12015893; 16920215)

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