Anticorps Recombinant de lapin anti-CD80

CD80 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain et plus (1)

Applications

FC

Conjugaison

Non conjugué

CloneNo.

242913B11

N° de cat : 98384-1-RR

Synonymes

Activation B7 1 antigen, Activation B7-1 antigen, B7, B7 1, B7-1

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Galerie de données de validation

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  FC experiment of Raji using 98384-1-RR

  1x10^6 Raji (left) or HUVEC cells (right) were surface stained with 0.25 ug Anti-Human CD80 Rabbit RecAb (98384-1-RR, Clone: 242913B11) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: cellules Raji,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

98384-1-RR cible CD80 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Réactivité citée: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: CD80 molecule
• Masse moléculaire calculée: 33 kDa
• Numéro d’acquisition GenBank: NM_005191
• Symbole du gène: CD80
• Identification du gène (NCBI): 941
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2 - 8°C. Stable for one year after shipment.

Informations générales

CD80 (also known as B7-1) is a type I membrane protein that is a member of the immunoglobulin superfamily, with an extracellular immunoglobulin constant-like domain and a variable-like domain required for receptor binding. It is expressed on antigen-presenting cells (APCs), including B cells, dendritic cells, monocytes, and macrophages. CD80 is the receptor for the proteins CD28 and CTLA-4 found on the surface of T-cells. It is involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. CD80 also acts as a cellular attachment receptor for adenovirus subgroup B. (PMID: 7545666; 12015893; 16920215)

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