Anticorps Recombinant de lapin anti-CD80

CD80 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

CoraLite® Plus 647 Fluorescent Dye

CloneNo.

242913B11

N° de cat : CL647-98384

Synonymes

Activation B7 1 antigen, Activation B7-1 antigen, B7, B7 1, B7-1

---

Galerie de données de validation

• 

  FC experiment of Raji using CL647-98384

  1x10^6 Raji (left) or HUVEC cells (right) were surface stained with 5 ul CoraLite® Plus 647 Anti-Human CD80 Rabbit RecAb (CL647-98384, Clone: 242913B11) (red) or CoraLite® Plus 647 Rabbit IgG Isotype Control RecAb (CL647-98136, Clone: 240953C9) (blue). Cells were not fixed.

---

Applications testées

• Résultats positifs en cytométrie: cellules Raji,

Dilution recommandée

Application	Dilution
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Informations sur le produit

CL647-98384 cible CD80 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CD80 Protéine recombinante Eg3505
• Nom complet: CD80 molecule
• Masse moléculaire calculée: 33 kDa
• Numéro d’acquisition GenBank: NM_005191
• Symbole du gène: CD80
• Identification du gène (NCBI): 941
• Conjugaison: CoraLite® Plus 647 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 654 nm / 674 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide and 0.5% BSA
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

CD80 (also known as B7-1) is a type I membrane protein that is a member of the immunoglobulin superfamily, with an extracellular immunoglobulin constant-like domain and a variable-like domain required for receptor binding. It is expressed on antigen-presenting cells (APCs), including B cells, dendritic cells, monocytes, and macrophages. CD80 is the receptor for the proteins CD28 and CTLA-4 found on the surface of T-cells. It is involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. CD80 also acts as a cellular attachment receptor for adenovirus subgroup B. (PMID: 7545666; 12015893; 16920215)

{{ptg:RelatedPrimaryAntibodies}}