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Anticorps Polyclonal de lapin anti-CD80

CD80 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 14292-1-PBS

Synonymes

BB1, B7-1, B7 1, B7, Activation B7-1 antigen

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using CD80 Polyclonal antibody (14292-1-AP)

    WB analysis using 14292-1-AP (same clone as 14292-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 14292-1-AP (CD80/B7-1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14292-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of human peripheral blood leukocyte using CD80 Polyclonal antibody (14292-1-AP)

    WB analysis of human peripheral blood leukocyte using 14292-1-AP (same clone as 14292-1-PBS)

    Human peripheral blood leukocyte were subjected to SDS PAGE followed by western blot with 14292-1-AP (CD80/B7-1 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14292-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of RAW 264.7 cells using CD80 Polyclonal antibody (14292-1-AP)

    WB analysis of RAW 264.7 using 14292-1-AP (same clone as 14292-1-PBS)

    RAW 264.7 cells were subjected to SDS PAGE followed by western blot with 14292-1-AP (CD80/B7-1 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14292-1-PBS in a different storage buffer formulation.

Informations sur le produit

14292-1-PBS cible CD80 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

Réactivité Humain, souris
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène CD80 Protéine recombinante Ag5615
Nom complet CD80 molecule
Masse moléculaire calculée 33 kDa
Poids moléculaire observé 60 kDa
Numéro d’acquisition GenBankBC042665
Symbole du gène CD80
Identification du gène (NCBI) 941
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CD80 (also known as B7-1) is a type I membrane protein that is a member of the immunoglobulin superfamily, with an extracellular immunoglobulin constant-like domain and a variable-like domain required for receptor binding. It is expressed on antigen-presenting cells (APCs), including B cells, dendritic cells, monocytes, and macrophages. CD80 is the receptor for the proteins CD28 and CTLA-4 found on the surface of T-cells. It is involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. CD80 also acts as a cellular attachment receptor for adenovirus subgroup B. (PMID: 7545666; 12015893; 16920215)

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