Anticorps Recombinant de lapin anti-CD83

CD83 Recombinant Antibody for WB, Sandwich ELISA, Indirect ELISA, Sample test

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Sandwich ELISA, Indirect ELISA, Sample test

Conjugaison

Non conjugué

CloneNo.

241855G5

N° de cat : 84796-3-PBS

Synonymes

241855G5, B cell activation protein, B-cell activation protein, BL11, CD83 antigen

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Galerie de données de validation

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  WB analysis using 84796-3-RR (same clone as 84796-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84796-3-RR (CD83 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84796-3-PBS in a different storage buffer formulation.

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  Sandwich ELISA standard curve of MP01570-3

  Sandwich ELISA standard curve of MP01570-3, Human CD83 Recombinant Matched Antibody Pair - PBS only. 84796-4-PBS was coated to a plate as the capture antibody and incubated with serial dilutions of standard Eg2033. 84796-3-PBS was HRP conjugated as the detection antibody. Range: 19.5-1250 pg/mL

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  Sample test of MP01570-3

  Serum of six individual healthy human donors was measured. The human CD83 concentration of detected samples was determined to be 372.6 pg/mL with a range of 167.8 - 934.1 pg/mL.

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Informations sur le produit

84796-3-PBS cible CD83 dans les applications de WB, Sandwich ELISA, Indirect ELISA, Sample test et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CD83 Protéine recombinante Eg2033
• Nom complet: CD83 molecule
• Masse moléculaire calculée: 23 kDa
• Poids moléculaire observé: 40-45 kDa
• Numéro d’acquisition GenBank: NM_004233.4
• Symbole du gène: CD83
• Identification du gène (NCBI): 9308
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CD83 is a member of the immunoglobulin (Ig) superfamily, consisting of an extracellular V-type Ig-like domain, a transmembrane domain, and a cytoplasmic tail. CD83 is one of the most prominent markers for fully matured dendritic cells (DCs) (PMID: 17334966). It is also found on the surface of other activated hematopoietic cells, including lymphocytes, monocytes, macrophages, and neutrophils (PMID: 31231400; 17334966). CD83 regulates the maturation, activation, and homeostasis of numerous immune cells (PMID: 31231400; 32362900). CD83 can also expressed as a soluble form. Soluble CD83 can bind to DCs and inhibit their maturation (PMID: 17334966; 12403928).

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