Anticorps Recombinant de lapin anti-CD83

CD83 Recombinant Antibody for FC

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain, primates non humains

Applications

FC

Conjugaison

Biotin

CloneNo.

HB15e

N° de cat : Biotin-65581

Synonymes

B cell activation protein, B-cell activation protein, BL11, CD83 antigen, CD83 molecule

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Galerie de données de validation

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  FC experiment of human monocyte-derived mature dendritic cells using Biotin-65581

  1x10^6 human monocyte-derived mature dendritic cells were surface stained with 0.25 ug Biotin Anti-Human CD83 (HB15e) Mouse IgG2a RecAb (Biotin-65581, Clone: HB15e) (red) or unstained (blue), and CoraLite®488-conjugated streptavidin. Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: human monocyte-derived mature dendritic cells

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

Biotin-65581 cible CD83 dans les applications de FC et montre une réactivité avec des échantillons Humain, primates non humains

• Réactivité: Humain, primates non humains
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Cellules Cos humaines transfectées par CD83
• Nom complet: CD83 molecule
• Masse moléculaire calculée: 205 aa, 23 kDa
• Numéro d’acquisition GenBank: BC030830
• Symbole du gène: CD83
• Identification du gène (NCBI): 9308
• Conjugaison: Biotin
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

CD83 is a member of the immunoglobulin (Ig) superfamily, consisting of an extracellular V-type Ig-like domain, a transmembrane domain, and a cytoplasmic tail. CD83 is one of the most prominent markers for fully matured dendritic cells (DCs) (PMID: 17334966). It is also found on the surface of other activated hematopoietic cells, including lymphocytes, monocytes, macrophages, and neutrophils (PMID: 31231400; 17334966). CD83 regulates the maturation, activation, and homeostasis of numerous immune cells (PMID: 31231400; 32362900). CD83 can also expressed as a soluble form. Soluble CD83 can bind to DCs and inhibit their maturation (PMID: 17334966; 12403928).

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