Anticorps Recombinant de lapin anti-CD86
CD86 Recombinant Antibody for FC
Hôte / Isotype
Lapin / IgG
Réactivité testée
Humain
Applications
FC
Conjugaison
APC Fluorescent Dye
CloneNo.
240429C6
N° de cat : APC-FcA98043
Synonymes
Galerie de données de validation
Applications testées
| Résultats positifs en cytométrie | CMSP humaines, | 
Dilution recommandée
| Application | Dilution | 
|---|---|
| This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood. | |
| Sample-dependent, check data in validation data gallery | |
Informations sur le produit
APC-FcA98043 cible CD86 dans les applications de FC et montre une réactivité avec des échantillons Humain
| Réactivité | Humain | 
| Hôte / Isotype | Lapin / IgG | 
| Clonalité | Recombinant | 
| Type | Anticorps | 
| Immunogène | CD86 Protéine recombinante Eg0966 | 
| Nom complet | CD86 molecule | 
| Masse moléculaire calculée | 329 aa, 38 kDa | 
| Numéro d’acquisition GenBank | NM_175862 | 
| Symbole du gène | CD86 | 
| Identification du gène (NCBI) | 942 | 
| Conjugaison | APC Fluorescent Dye | 
| Excitation/Emission maxima wavelengths | 650 nm / 660 nm | 
| Forme | Liquide | 
| Méthode de purification | Purification par protéine A | 
| Tampon de stockage | PBS with 0.09% sodium azide and 0.5% BSA | 
| Conditions de stockage | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. | 
Informations générales
CD86 (also known as B7-2) is a costimulatory molecule belonging to the immunoglobulin superfamily. Primarily expressed on antigen-presenting cells (APCs), including B cells, dendritic cells, and macrophages, CD86 is the ligand for two proteins at the cell surface of T cells, CD28 antigen and CTLA-4. Binding of CD86 with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of CD86 with CTLA-4 negatively regulates T-cell activation and diminishes the immune response. (PMID: 7513726; 1847722; 11029388; 27591335)
Protocole
| Product Specific Protocols | |
|---|---|
| FC protocol for APC CD86 antibody APC-FcA98043 | Download protocol | 
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols | 

