Anticorps Recombinant de lapin anti-CD8a

CD8a Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

243018F5

N° de cat : 86063-1-PBS

Synonymes

CD8, CD8a molecule, Leu2, MAL, p32

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Galerie de données de validation

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  WB analysis using 86063-1-RR (same clone as 86063-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86063-1-RR (CD8A antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86063-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 86063-1-RR

  Biolayer interferometry (BLl) kinetic assays of 86063-1-RR against Human CD8a were performed. The affinity constant is 1.42 nM.

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Informations sur le produit

86063-1-PBS cible CD8a dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CD8a Protéine recombinante Eg0819
• Nom complet: CD8a molecule
• Masse moléculaire calculée: 26 kDa
• Poids moléculaire observé: 25 kDa
• Numéro d’acquisition GenBank: NM_001145873.1
• Symbole du gène: CD8A
• Identification du gène (NCBI): 925
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CD8 is a transmembrane glycoprotein that is predominantly expressed on the surface of cytotoxic T cells, and can also be found on natural killer cells, cortical thymocytes, and dendritic cells. CD8 serves as a co-receptor for the T cell receptor (TCR). Both CD8 and TCR recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. CD8 plays a role in T cell development and activation of mature T cells. This antibody is raised against 22-182 aa of human CD8a, the alpha chain of CD8 molecule.

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