Anticorps Recombinant de lapin anti-CD8b

CD8b Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

250480F2

N° de cat : 86024-1-PBS

Synonymes

Cd8b1, Ly-3, Lymphocyte antigen 3, Lyt3, Lyt-3

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Galerie de données de validation

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  WB analysis using 86024-1-RR (same clone as 86024-1-PBS)

  Mouse thymus tissue was subjected to SDS PAGE followed by western blot with 86024-1-RR (CD8 beta antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86024-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 86024-1-RR (same clone as 86024-1-PBS)

  Mouse spleen tissue was subjected to SDS PAGE followed by western blot with 86024-1-RR (CD8 beta antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86024-1-PBS in a different storage buffer formulation.

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Informations sur le produit

86024-1-PBS cible CD8b dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CD8b Protéine recombinante Eg4275
• Nom complet: CD8 antigen, beta chain 1
• Masse moléculaire calculée: 24 kDa
• Poids moléculaire observé: 26-30 kDa
• Numéro d’acquisition GenBank: NM_009858.2
• Symbole du gène: Cd8b1
• Identification du gène (NCBI): 12526
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CD8b (T-cell surface glycoprotein CD8 beta chain) is an integral membrane glycoprotein that forms disulfide-linked heterodimers with CD8a (CD8 alpha chain). The CD8 alpha/beta heterodimer is the predominant CD8 complex expressed on the cell surface (PMID: 1534146; 2111591). CD8 is a transmembrane glycoprotein predominantly expressed on cytotoxic T cells and can also be found on natural killer cells, cortical thymocytes, and dendritic cells. CD8 serves as a co-receptor for the T cell receptor (TCR). Both CD8 and TCR recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. CD8 plays a role in T cell development and activation of mature T cells.

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