Anticorps Recombinant de lapin anti-CD8b

CD8b Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

241326A7

N° de cat : 98103-1-PBS

Synonymes

CD8, 241326A7, Ly3, Leu2, CD8B1

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Galerie de données de validation

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  FC experiment of human PBMCs using 98103-1-RR (same clone as 98103-1-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD8b Rabbit Recombinant Antibody (98103-1-RR, Clone: 241326A7) or Isotype Control, and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with APC Anti-Human CD3. Cells were not fixed. This data was developed using the same antibody clone with 98103-1-PBS in a different storage buffer formulation.

• 

  FC experiment of human PBMCs using 98103-1-RR (same clone as 98103-1-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD8b Rabbit Recombinant Antibody (98103-1-RR, Clone: 241326A7)(red), or Isotype Control (blue) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98103-1-PBS in a different storage buffer formulation.

• 

  Affinity and Kinetic Characterization of 98103-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98103-1-RR against Human CD8b were performed. The affinity constant is below 1 pM.

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Informations sur le produit

98103-1-PBS cible CD8b dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: CD8b molecule
• Masse moléculaire calculée: 243 aa, 27 kDa
• Numéro d’acquisition GenBank: BC100913
• Symbole du gène: CD8B
• Identification du gène (NCBI): 926
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

CD8b (T-cell surface glycoprotein CD8 beta chain) is an integral membrane glycoprotein that forms disulfide-linked heterodimers with CD8a (CD8 alpha chain). The CD8 alpha/beta heterodimer is the predominant CD8 complex expressed on the cell surface (PMID: 1534146; 2111591). CD8 is a transmembrane glycoprotein predominantly expressed on the surface of cytotoxic T cells and can also be found on natural killer cells, cortical thymocytes, and dendritic cells. CD8 serves as a co-receptor for the T cell receptor (TCR). Both CD8 and TCR recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. CD8 plays a role in T cell development and activation of mature T cells.

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