Anticorps Recombinant de lapin anti-CD8b

CD8b Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Biotin

CloneNo.

241326A7

N° de cat : Biotin-98103

Synonymes

CD8, 241326A7, CD8b molecule, CD8B1, Leu2

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Galerie de données de validation

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  FC experiment of human PBMCs using Biotin-98103

  1x10^6 human PBMCs were surface stained with 5 ul Biotin Anti-Human CD8b Rabbit RecAb (Biotin-98103, Clone:241326A7) and PE-conjugated streptavidin, or unstained. Cells were co-stained with APC Anti-Human CD3 (UCHT1) Mouse IgG2a Recombinant Antibody (APC-65570, Clone: UCHT1). Cells were not fixed.

• 

  FC experiment of human PBMCs using Biotin-98103

  1x10^6 human PBMCs were surface stained with 5 ul Biotin Anti-Human CD8b Rabbit RecAb (Biotin-98103, Clone: 241326A7) and PE-conjugated streptavidin (red), or unstained (blue). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: CMSP humaines,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

Biotin-98103 cible CD8b dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: CD8b molecule
• Masse moléculaire calculée: 243 aa, 27 kDa
• Numéro d’acquisition GenBank: BC100913
• Symbole du gène: CD8B
• Identification du gène (NCBI): 926
• Conjugaison: Biotin
• Excitation/Emission maxima wavelengths: -
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS with 0.09% sodium azide and 0.5% BSA
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

CD8b (T-cell surface glycoprotein CD8 beta chain) is an integral membrane glycoprotein that forms disulfide-linked heterodimers with CD8a (CD8 alpha chain). The CD8 alpha/beta heterodimer is the predominant CD8 complex expressed on the cell surface (PMID: 1534146; 2111591). CD8 is a transmembrane glycoprotein predominantly expressed on the surface of cytotoxic T cells and can also be found on natural killer cells, cortical thymocytes, and dendritic cells. CD8 serves as a co-receptor for the T cell receptor (TCR). Both CD8 and TCR recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. CD8 plays a role in T cell development and activation of mature T cells.

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