Anticorps Recombinant de lapin anti-CD93

CD93 Recombinant Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242464D2

N° de cat : 84945-4-PBS

Synonymes

C1QR1, Matrix-remodeling-associated protein 4, C1qRp, C1qR(p), C1qR

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Galerie de données de validation

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  WB analysis of HUVEC using 84945-4-RR (same clone as 84945-4-PBS)

  HUVEC cells were subjected to SDS PAGE followed by western blot with 84945-4-RR (CD93 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84945-4-PBS in a different storage buffer formulation.

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  IHC staining of human tonsillitis using 84945-4-RR (same clone as 84945-4-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 84945-4-RR (CD93 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84945-4-PBS in a different storage buffer formulation.

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  IHC staining of human tonsillitis using 84945-4-RR (same clone as 84945-4-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 84945-4-RR (CD93 antibody) at dilution of 1:1000 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84945-4-PBS in a different storage buffer formulation.

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Informations sur le produit

84945-4-PBS cible CD93 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: CD93 molecule
• Masse moléculaire calculée: 69 kDa
• Poids moléculaire observé: 120 kDa
• Numéro d’acquisition GenBank: NM_012072.3
• Symbole du gène: CD93
• Identification du gène (NCBI): 22918
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CD93, also known as C1qR or C1qR(p), is a single-pass type I transmembrane glycoprotein and a member of the group 14 of the C-type lectin-like domain (CTLD) superfamily, which also includes endosialin/CD248, thrombomodulin, and CLEC14A (PMID: 31287944). CD93 consists of a C-type lectin-like domain, five EGF-like repeats, a mucin-like domain, a transmembrane domain and a cytoplasmic domain (PMID: 28912033). CD93 is mainly expressed on endothelial cells and has been reported to be expressed by neurons and various cells of the hematopoietic system, including monocytes, neutrophils, B cells, natural killer cells, platelets and hematopoietic stem cells (PMID: 37443812). CD93 plays a role in various physiological processes including angiogenesis, inflammation, and cell adhesion (PMID: 31287944).

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