Anticorps Recombinant de lapin anti-CD93

CD93 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

242464E6

N° de cat : 98337-1-PBS

Synonymes

C1QR1, 242464E6, C1qR, C1qR(p), C1qRp

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Galerie de données de validation

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  FC experiment of human PBMCs using 98337-1-RR (same clone as 98337-1-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD93 Rabbit RecAb (98337-1-RR, Clone: 242464E6) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with CoraLite® Plus 647 Anti-Human CD14. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98337-1-PBS in a different storage buffer formulation.

• 

  FC experiment of human PBMCs using 98337-1-RR (same clone as 98337-1-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD93 Rabbit RecAb (98337-1-RR, Clone: 242464E6) (red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98337-1-PBS in a different storage buffer formulation.

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Informations sur le produit

98337-1-PBS cible CD93 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CD93 Protéine recombinante Eg2794
• Nom complet: CD93 molecule
• Masse moléculaire calculée: 69 kDa
• Numéro d’acquisition GenBank: NM_012072.3
• Symbole du gène: CD93
• Identification du gène (NCBI): 22918
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

CD93, also known as C1qR or C1qR(p), is a single-pass type I transmembrane glycoprotein and a member of the group 14 of the C-type lectin-like domain (CTLD) superfamily, which also includes endosialin/CD248, thrombomodulin, and CLEC14A (PMID: 31287944). CD93 consists of a C-type lectin-like domain, five EGF-like repeats, a mucin-like domain, a transmembrane domain and a cytoplasmic domain (PMID: 28912033). CD93 is mainly expressed on endothelial cells and has been reported to be expressed by neurons and various cells of the hematopoietic system, including monocytes, neutrophils, B cells, natural killer cells, platelets and hematopoietic stem cells (PMID: 37443812). CD93 plays a role in various physiological processes including angiogenesis, inflammation, and cell adhesion (PMID: 31287944).

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