Anticorps Monoclonal anti-CD95

CD95 Monoclonal Antibody for FC

Hôte / Isotype

Mouse / IgG1, kappa

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

DX2

N° de cat : 65071-1-Ig

Synonymes

ALPS1A, APO 1, Apo 1 antigen, APT1, CD95, FAS, FAS1, FASLG receptor, FASTM, TNFRSF6

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Galerie de données de validation

• 

  FC experiment of human peripheral blood lymphocytes using 65071-1-Ig

  1X10^6 human peripheral blood lymphocytes were surface stained with 0.25 ug Anti-Human CD95 (65071-1-Ig, Clone:DX2) and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L) at dilution 1:1000 (green), or stained with 0.25 ug mouse IgG1 isotype control and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L) at dilution 1:1000 (black). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: lymphocytes de sang périphérique humain,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

65071-1-Ig cible CD95 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG1, kappa
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: Cellules L humaines transfectées par CD95
• Nom complet: Fas (TNF receptor superfamily, member 6)
• Masse moléculaire calculée: 35-38 kDa
• Numéro d’acquisition GenBank: BC012479
• Symbole du gène: Fas/CD95
• Identification du gène (NCBI): 355
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité
• Tampon de stockage: Borate buffered saline
• Conditions de stockage: Store at 2-8°C. Stable for one year after shipment.

Informations générales

Fas (CD95/APO-1) is a transmembrane glycoprotein belonging to the tumor necrosis factor (TNF) receptor superfamily. It can mediate apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains, leading to the formation of the death-inducing signaling complex (DISC). FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.

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