Anticorps Recombinant de lapin anti-CD98/SLC3A2

CD98/SLC3A2 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

241247F1

N° de cat : 98128-1-RR

Synonymes

Mdu1, CD98, Amino acid transporter heavy chain SLC3A2, 4F2hc, 4F2 cell-surface antigen heavy chain

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Galerie de données de validation

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  FC experiment of mouse splenocytes using 98128-1-RR

  1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CD98/SLC3A2 Rabbit Recombinant Antibody (98128-1-RR, Clone: 241247F1) or 0.25 ug Isotype Control, and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with APC Anti-Mouse TER-119 (TER-119) (APC-65149, Clone: TER-119). Cells were not fixed.

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  FC experiment of mouse splenocytes using 98128-1-RR

  1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CD98 Rabbit Recombinant Antibody (98128-1-RR, Clone: 241247F1) (red) or 0.25 ug Isotype Control (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

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  Affinity and Kinetic Characterization of 98128-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98128-1-RR against Mouse CD98 were performed. The affinity constant is 7.51 nM.

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Applications testées

• Résultats positifs en cytométrie: splénocytes de souris,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

98128-1-RR cible CD98/SLC3A2 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
• Masse moléculaire calculée: 58 kDa
• Numéro d’acquisition GenBank: NM_008577.4
• Symbole du gène: CD98/SLC3A2
• Identification du gène (NCBI): 17254
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2 - 8°C. Stable for one year after shipment.

Informations générales

CD98 is a cell-surface heterodimer consisting of a heavy chain (CD98hc) and a light chain. CD98hc also interacts with certain integrin b-subunits to regulate cell migration, survival, proliferation, and adhesion/polarity. CD98hc is overexpressed on the cell surface of many cancers and increased CD98hc expression is associated with the development and progression of tumors.(PMID:25084765). This protein has 4 isoforms with the molecular mass of 58-71 kDa and can be detected 85-94 kDa due to glycosylation. The glycosylated CD98hc can links to a non-glycosylated light chain (~40 kDa) via a disulfide bond to form a heterodimeric CD98 antigen with molecular mass of 120-130 kDa (PMID: 14770309).

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