Anticorps Recombinant de lapin anti-CD98/SLC3A2

CD98/SLC3A2 Recombinant Antibody for FC

Hôte / Isotype

Lapin / scFv

Réactivité testée

Humain

Applications

FC

Conjugaison

Biotin

CloneNo.

241755D6

N° de cat : Biotin-SF98190

Synonymes

CD98, SLC3A2, 4F2 cell-surface antigen heavy chain, Amino acid transporter heavy chain SLC3A2, MDU1

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Galerie de données de validation

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  FC experiment of human PBMCs using Biotin-SF98190

  1x10^6 human PBMCs were surface stained with 0.25 ug Biotin Anti-Human CD98/SLC3A2 Rabbit scFv Antibody (Biotin-SF98190, Clone: 241755D6) or 0.25 ug Isotype Control, and PE Streptavidin (Cat.No. PF00021). Cells were not fixed.

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  FC experiment of human PBMCs using Biotin-SF98190

  1x10^6 human PBMCs were surface stained with 0.25 ug Biotin Anti-Human CD98/SLC3A2 Rabbit scFv Antibody (Biotin-SF98190, Clone: 241755D6)(red) or 0.25 ug Isotype Control (blue), and PE Streptavidin (Cat.No. PF00021). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: CMSP humaines,

Dilution recommandée

• Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in a 100 µl suspension

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Informations sur le produit

Biotin-SF98190 cible CD98/SLC3A2 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / scFv
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CD98/SLC3A2 Protéine recombinante Eg1948
• Nom complet: solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
• Masse moléculaire calculée: 68 kDa
• Numéro d’acquisition GenBank: NM_002394.5
• Symbole du gène: CD98
• Identification du gène (NCBI): 6520
• Conjugaison: Biotin
• Excitation/Emission maxima wavelengths: -
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA
• Conditions de stockage: Stocker à -20 °C. Éviter toute exposition à la lumière. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

CD98 is a 125-kDa type II membrane glycoprotein heterodimer composed of a 40-kDa non-glycosylated light chain (amino-acid transporter, encoded by the SLC7A5) and an 85-kDa glycosylated heavy chain (CD98hc, encoded by the SLC3A2) (PMID: 11507094). CD98hc also interacts with certain integrin b-subunits to regulate cell migration, survival, proliferation, and adhesion/polarity. CD98hc is overexpressed on the cell surface of many cancers and increased CD98hc expression is associated with the development and progression of tumors.(PMID:25084765). Molecular orientation studies have demonstrated that the C-terminal tail of human CD98 (hCD98), which contains a PDZ-binding domain, is extracellular (PMID: 18625289).

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