Anticorps Monoclonal anti-CDK5R1
CDK5R1 Monoclonal Antibody for WB, IHC, ELISA
Hôte / Isotype
Mouse / IgG2b
Réactivité testée
Humain, Lapin, porc, rat, souris
Applications
WB, IHC, IF, CoIP, ELISA
Conjugaison
Non conjugué
CloneNo.
1A3A5
N° de cat : 67503-1-Ig
Synonymes
Galerie de données de validation
Applications testées
| Résultats positifs en WB | tissu de cervelet de porc, tissu cérébral de porc, tissu cérébral de rat, tissu cérébral de souris, tissu de cervelet de souris |
| Résultats positifs en IHC | tissu cérébral de souris, tissu cérébral de rat il est suggéré de démasquer l'antigène avec un tampon de TE buffer pH 9.0; (*) À défaut, 'le démasquage de l'antigène peut être 'effectué avec un tampon citrate pH 6,0. |
Dilution recommandée
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:5000-1:50000 |
| Immunohistochimie (IHC) | IHC : 1:200-1:800 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, check data in validation data gallery | |
Applications publiées
| WB | See 4 publications below |
| IHC | See 1 publications below |
| IF | See 2 publications below |
| CoIP | See 1 publications below |
Informations sur le produit
67503-1-Ig cible CDK5R1 dans les applications de WB, IHC, IF, CoIP, ELISA et montre une réactivité avec des échantillons Humain, Lapin, porc, rat, souris
| Réactivité | Humain, Lapin, porc, rat, souris |
| Réactivité citée | Humain, souris |
| Hôte / Isotype | Mouse / IgG2b |
| Clonalité | Monoclonal |
| Type | Anticorps |
| Immunogène | CDK5R1 Protéine recombinante Ag13152 |
| Nom complet | cyclin-dependent kinase 5, regulatory subunit 1 (p35) |
| Masse moléculaire calculée | 34 kDa |
| Poids moléculaire observé | 34 kDa |
| Numéro d’acquisition GenBank | BC020580 |
| Symbole du gène | CDK5R1 |
| Identification du gène (NCBI) | 8851 |
| Conjugaison | Non conjugué |
| Forme | Liquide |
| Méthode de purification | Purification par protéine A |
| Tampon de stockage | PBS with 0.02% sodium azide and 50% glycerol |
| Conditions de stockage | Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA. |
Informations générales
Cyclin dependent kinase-5 (Cdk5), is an atypical but essential member of the Cdk family of proline-directed serine/threonine kinases. CDK5R1 encodes p35, a specific activator of the serine/threonine kinase CDK5, which plays a central role in neuronal migration and differentiation during central nervous system development. The p35 form of this protein is proteolytically cleaved by calpain, generating a p25 form.
Protocole
| Product Specific Protocols | |
|---|---|
| WB protocol for CDK5R1 antibody 67503-1-Ig | Download protocol |
| IHC protocol for CDK5R1 antibody 67503-1-Ig | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
Nat Commun GRAMD1B is a regulator of lipid homeostasis, autophagic flux and phosphorylated tau | ||
J Pharm Anal Histone deacetylase inhibitor pracinostat suppresses colorectal cancer by inducing CDK5-Drp1 signaling-mediated peripheral mitofission | ||
Mol Ther Nucleic Acids Implications of miR-148a-3p/p35/PTEN signaling in tau hyperphosphorylation and autoregulatory feedforward of Akt/CREB in Alzheimer's disease. | ||
Cancer Lett CDK5RAP3 is a novel super-enhancer-driven gene activated by master TFs and regulates ER-Phagy in neuroblastoma | ||
Sci China Life Sci FSD1 inhibits glioblastoma diffuse infiltration through restriction of HDAC6-mediated microtubule deacetylation | ||
Acta Pharm Sin B CDK5-triggered G6PD phosphorylation at threonine 91 facilitating redox homeostasis reveals a vulnerability in breast cancer |
Avis
The reviews below have been submitted by verified Proteintech customers who received an incentive for providing their feedback.
FH Jia Kang (Verified Customer) (09-05-2025) | The antibody worked rather well, providing clear images under the microscope. No particular issue with this specific antibody.
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