Anticorps Polyclonal de lapin anti-CDKL5

CDKL5 Polyclonal Antibody for WB, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 12973-1-PBS

Synonymes

cyclin dependent kinase like 5, Cyclin-dependent kinase-like 5, EC:2.7.11.22, ISSX, Serine/threonine-protein kinase 9

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Galerie de données de validation

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  WB analysis using 12973-1-AP (same clone as 12973-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 12973-1-AP (CDKL5 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12973-1-PBS in a different storage buffer formulation.

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  WB analysis using 12973-1-AP (same clone as 12973-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 12973-1-AP (CDKL5 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12973-1-PBS in a different storage buffer formulation.

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  WB analysis of HepG2 using 12973-1-AP (same clone as 12973-1-PBS)

  HepG2 cells were subjected to SDS PAGE followed by western blot with 12973-1-AP (CDKL5 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12973-1-PBS in a different storage buffer formulation.

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  IP experiment of mouse brain using 12973-1-AP (same clone as 12973-1-PBS)

  IP result of anti-CDKL5 (IP:12973-1-AP, 4ug; Detection:12973-1-AP 1:300) with mouse brain tissue lysate 3200 ug. This data was developed using the same antibody clone with 12973-1-PBS in a different storage buffer formulation.

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Informations sur le produit

12973-1-PBS cible CDKL5 dans les applications de WB, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: CDKL5 Protéine recombinante Ag3531
• Nom complet: cyclin-dependent kinase-like 5
• Masse moléculaire calculée: 1030 aa, 114 kDa
• Poids moléculaire observé: 100-110 kDa
• Numéro d’acquisition GenBank: BC036091
• Symbole du gène: CDKL5
• Identification du gène (NCBI): 6792
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Cyclin dependent kinase like 5 (CDKL5) may regulate ciliogenesis and neuronal morphogenesis. It has been reported that CDKL5 is associated with epileptic seizures, severe intellectual disability, and autistic features. The CDKL5 protein is a kinase that regulates key phosphorylation events vital to the development of the complex neuronal network of the brain.

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