Anticorps Recombinant de lapin anti-CEACAM1/3/6 (CD66a/c/d)

CEACAM1/3/6 (CD66a/c/d) Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

APC Fluorescent Dye

CloneNo.

240497E12

N° de cat : APC-FcA98061

Synonymes

CEACAM1, CEACAM1/CD66a, Biliary glycoprotein 1, BGPI, BGP-1

---

Galerie de données de validation

• 

  FC experiment of human peripheral blood leukocytes using APC-FcA98061

  1x10^6 human peripheral blood leukocytes were surface stained with FcZero-rAb™ PE Anti-Human CD16 and 5 ul APC Anti-Human CEACAM1/3/6 (CD66a/c/d) Rabbit RecAb (APC-FcA98061, Clone:240497E12) or 5 ul APC Rabbit IgG Isotype Control RecAb (APC-FcA98136, Clone: 240953C9). Cells were not fixed.

• 

  FC experiment of human peripheral blood leukocytes using APC-FcA98061

  1x10^6 human peripheral blood leukocytes were surface stained with 5 ul APC Anti-Human CEACAM1/3/6 (CD66a/c/d) Rabbit RecAb (APC-FcA98061, Clone:240497E12) or 5 ul APC Rabbit IgG Isotype Control RecAb (APC-FcA98136, Clone: 240953C9). Cells were not fixed.

---

Applications testées

• Résultats positifs en cytométrie: human peripheral blood leukocytes,

Dilution recommandée

Application	Dilution
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Informations sur le produit

APC-FcA98061 cible CEACAM1/3/6 (CD66a/c/d) dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
• Masse moléculaire calculée: 526 aa, 58 kDa
• Numéro d’acquisition GenBank: BC014473
• Symbole du gène: CEACAM1
• Identification du gène (NCBI): 634
• Conjugaison: APC Fluorescent Dye
• Excitation/Emission maxima wavelengths: 650 nm / 660 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide and 0.5% BSA
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

CEACAM1, also known as CD66a or BGP (biliary glycoprotein), is a member of the cacinoembryonic antigen (CEA) family which belongs to the immunoglobulin superfamily of cell adhesion molecules (PMID: 16919437). CEACAMs play major roles in cell-cell and cell-ECM adhesion and have been implicated in the control of cell proliferation, angiogenesis, and tissue remodeling (PMID: 23021083). CEACAM1 is a transmembrane glycoprotein that is expressed on epithelial, endothelial, and immune cells (PMID: 30314283). CEACAM1 has been demonstrated to play a role in morphogenesis, apoptosis, angiogenesis, cell proliferation, cell motility, fibrosis, and immunity (PMID: 31604530). This antibody is raised against 35-428 aa of human CEACAM1/CD66a and can cross-react with CEACAM6/CD66c and CEACAM3/CD66d.

{{ptg:RelatedPrimaryAntibodies}}