Anticorps Polyclonal de lapin anti-CEACAM16

CEACAM16 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 32196-1-PBS

Synonymes

Carcinoembryonic Antigen Related Cell Adhesion Molecule 16, Carcinoembryonic antigen-like 2, Carcinoembryonic antigen-related cell adhesion molecule 16, CEA Cell Adhesion Molecule 16, Tectorial Membrane Component , DFNA4B

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Galerie de données de validation

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  WB analysis using 32196-1-AP (same clone as 32196-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 32196-1-AP (CEACAM16 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32196-1-PBS in a different storage buffer formulation.

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  IHC staining of human urothelial carcinoma using 32196-1-AP (same clone as 32196-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human urothelial carcinoma tissue slide using 32196-1-AP (CEACAM16 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 32196-1-PBS in a different storage buffer formulation.

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  IHC staining of human placenta using 32196-1-AP (same clone as 32196-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 32196-1-AP (CEACAM16 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 32196-1-PBS in a different storage buffer formulation.

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Informations sur le produit

32196-1-PBS cible CEACAM16 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: CEACAM16 Protéine recombinante Ag37542
• Nom complet: carcinoembryonic antigen-related cell adhesion molecule 16
• Poids moléculaire observé: 48 kDa
• Numéro d’acquisition GenBank: BC156855
• Symbole du gène: CEACAM16
• Identification du gène (NCBI): 388551
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CEACAM16 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 16) is a member of the CEA family of cell adhesion molecules. It is a critical component of the tectorial membrane in the inner ear, playing a significant role in maintaining hearing function. Mutations in the CEACAM16 gene are associated with autosomal dominant nonsyndromic hearing loss (DFNA4B), characterized by progressive high-frequency hearing impairment. Research has shown that loss or dysfunction of CEACAM16 leads to structural abnormalities in the tectorial membrane, thereby affecting hearing. The identification of CEACAM16 has provided important insights into the genetic basis of hereditary hearing loss and has implications for the diagnosis and treatment of hearing disorders.

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