Anticorps Polyclonal de lapin anti-CEACAM21

CEACAM21 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 17209-1-PBS

Synonymes

Carcinoembryonic antigen-related cell adhesion molecule 21, UNQ3098/PRO10075

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Galerie de données de validation

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  WB analysis using 17209-1-AP (same clone as 17209-1-PBS)

  Mouse liver tissue lysate was subjected to SDS PAGE followed by western blot with 17209-1-AP (CEACAM21 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17209-1-PBS in a different storage buffer formulation.

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  IHC staining of human placenta using 17209-1-AP (same clone as 17209-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 17209-1-AP (CEACAM21 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17209-1-PBS in a different storage buffer formulation.

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  IHC staining of human placenta using 17209-1-AP (same clone as 17209-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 17209-1-AP (CEACAM21 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17209-1-PBS in a different storage buffer formulation.

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Informations sur le produit

17209-1-PBS cible CEACAM21 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: CEACAM21 Protéine recombinante Ag10992
• Nom complet: carcinoembryonic antigen-related cell adhesion molecule 21
• Masse moléculaire calculée: 32 kDa
• Poids moléculaire observé: 30 kDa
• Numéro d’acquisition GenBank: BC012001
• Symbole du gène: CEACAM21
• Identification du gène (NCBI): 90273
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Carcinoembryonic antigen-related cell adhesion molecule 21 (CEACAM21) is a member of the CEACAM family that has diverse functions in cell adhesion, in intracellular and intercellular signaling, and during complex biological processes such as cancer progression, inflammation, angiogenesis, and metastasis (PMID: 23903773; 32488569). CEACAM21 acts as a heterophilic ligand for TIM-3, leading to the dissociation of Bat3 and increasing proximal TCR signaling and proapoptotic protein expression in late effector T cells, thereby mediating T cell suppression (PMID: 38490257).

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