Anticorps Recombinant de lapin anti-CEACAM6/CD66c

CEACAM6/CD66c Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

241997G1

N° de cat : 98329-3-PBS

Synonymes

CEACAM6, NCA, CEAL, CD66c, Carcinoembryonic antigen-related cell adhesion molecule 6

---

Galerie de données de validation

• 

  FC experiment of human peripheral blood leukocytes using 98329-3-RR (same clone as 98329-3-PBS)

  1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human CEACAM6/CD66c Rabbit RecAb (98329-3-RR, Clone: 241997G1) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-conjugated Goat Anti-Rabbit IgG. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98329-3-PBS in a different storage buffer formulation.

• 

  FC experiment of human peripheral blood leukocytes using 98329-3-RR (same clone as 98329-3-PBS)

  1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human CEACAM6/CD66c Rabbit RecAb (98329-3-RR, Clone:241997G1) (red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-conjugated Goat Anti-Rabbit IgG. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98329-3-PBS in a different storage buffer formulation.

---

Informations sur le produit

98329-3-PBS cible CEACAM6/CD66c dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
• Masse moléculaire calculée: 37 kDa
• Numéro d’acquisition GenBank: BC005008
• Symbole du gène: CEACAM6
• Identification du gène (NCBI): 4680
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) belong to the immunoglobulin superfamily of cell adhesion molecules. CEACAMs play major roles in cell-cell and cell-ECM adhesion and have been implicated in controlling cell proliferation, angiogenesis, and tissue remodeling (PMID: 23021083). CEACAM6, also known as CD66c, is a glycosylphosphatidylinositol (GPI)-linked cell surface protein that belongs to the CEACAM family of the immunoglobulin superfamily (PMID: 23903773). It is normally expressed on the surface of myeloid and epithelial surfaces and upregulated preferentially at the apical/luminal membranes of many tumors (PMID: 27595061; 35082925). CEACAM6 plays an important role in cell adhesion, proliferation, tumorigenesis, metastasis, and immunity (PMID: 31797958).

{{ptg:RelatedPrimaryAntibodies}}