Anticorps Recombinant de lapin anti-CEACAM6/CD66c

CEACAM6/CD66c Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

CoraLite®594 Fluorescent Dye

CloneNo.

241997G1

N° de cat : CL594-98329-3

Synonymes

CEACAM6, 241997G1, Carcinoembryonic antigen-related cell adhesion molecule 6, CD66c, CEAL

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Galerie de données de validation

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  FC experiment of human peripheral blood leukocytes using CL594-98329-3

  1x10^6 human peripheral blood leukocytes were surface stained with 5 ul CoraLite®594 Anti-Human CEACAM6/CD66c Rabbit RecAb (CL594-98329-3, Clone: 241997G1) or CoraLite®594 Rabbit IgG Isotype Control RecAb (CL594-98136, Clone: 240953C9). Cells were incubated with FC Receptor Block prior to fixing and staining. Cells were not fixed.

• 

  FC experiment of human peripheral blood leukocytes using CL594-98329-3

  1x10^6 human peripheral blood leukocytes were surface stained with 5 ul CoraLite®594 Anti-Human CEACAM6/CD66c Rabbit RecAb (CL594-98329-3, Clone: 241997G1) (red) or CoraLite®594 Rabbit IgG Isotype Control RecAb (CL594-98136, Clone: 240953C9) (blue). Cells were incubated with FC Receptor Block prior to fixing and staining. Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: human peripheral blood leukocytes

Dilution recommandée

Application	Dilution
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Informations sur le produit

CL594-98329-3 cible CEACAM6/CD66c dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CEACAM6/CD66c Protéine recombinante Eg2450
• Nom complet: carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
• Masse moléculaire calculée: 37 kDa
• Numéro d’acquisition GenBank: BC005008
• Symbole du gène: CEACAM6
• Identification du gène (NCBI): 4680
• Conjugaison: CoraLite®594 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 588 nm / 604 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide and 0.5% BSA
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) belong to the immunoglobulin superfamily of cell adhesion molecules. CEACAMs play major roles in cell-cell and cell-ECM adhesion and have been implicated in controlling cell proliferation, angiogenesis, and tissue remodeling (PMID: 23021083). CEACAM6, also known as CD66c, is a glycosylphosphatidylinositol (GPI)-linked cell surface protein that belongs to the CEACAM family of the immunoglobulin superfamily (PMID: 23903773). It is normally expressed on the surface of myeloid and epithelial surfaces and upregulated preferentially at the apical/luminal membranes of many tumors (PMID: 27595061; 35082925). CEACAM6 plays an important role in cell adhesion, proliferation, tumorigenesis, metastasis, and immunity (PMID: 31797958).

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