Anticorps Recombinant de lapin anti-CEACAM5/8 (CD66b/e)

CEACAM5/8 (CD66b/e) Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Biotin

CloneNo.

230353B7

N° de cat : Biotin-98012

Synonymes

CD66e, CEACAM5, CEACAM5/CD66e, CEACAM8/CD66b, CD66b

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Galerie de données de validation

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  FC experiment of human peripheral blood leukocytes using Biotin-98012

  1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Biotin Anti-Human CEACAM5/8 (CD66b/e) Rabbit Recombinant Antibody (Biotin-98012, Clone: 230353B7) and CoraLite®488-conjugated streptavidin, or unstained cells. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: CMSP humaines

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

Biotin-98012 cible CEACAM5/8 (CD66b/e) dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CEACAM5/8 (CD66b/e) Protéine recombinante Eg32133
• Nom complet: CEACAM5/8 (CD66b/e)
• Identification du gène (NCBI): 1088
• Conjugaison: Biotin
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) belong to the immunoglobulin superfamily of cell adhesion molecules. CEACAMs play major roles in cell-cell and cell-ECM adhesion and have been implicated in controlling cell proliferation, angiogenesis, and tissue remodeling (PMID: 23021083). Carcinoembryonic antigen (CEA), also known as CEACAM5 or CD66e mainly serves as a cell adhesion molecule mediating intercellular contact by both homophilic and heterophilic binding (PMID: 21731662). CEACAM8, also known as CD66b, CGM6 or NCA-95, is a glycosylphosphatidylinositol (GPI)-linked glycoprotein expressed on granulocytes and is involved in regulating adhesion and activation of eosinophils (PMID: 8104998; 18056392; 18056392). This antibody is raised against 35-319 aa of human CEACAM8/CD66b and can cross-react with CEACAM5/CD66e.

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