Anticorps Recombinant de lapin anti-CEACAM5/8 (CD66b/e)

CEACAM5/8 (CD66b/e) Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

CoraLite® Plus 750 Fluorescent Dye

CloneNo.

230353B7

N° de cat : CL750-98012

Synonymes

CD66b, CEACAM8, CD 67, CD 66b, Carcinoembryonic antigen-related cell adhesion molecule 8

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Galerie de données de validation

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  FC experiment of human peripheral blood leukocytes using CL750-98012

  1x10^6 human peripheral blood leukocytes were surface stained with 5 ul CoraLite® Plus 750 Anti-Human CEACAM5/8 (CD66b/e) Rabbit Recombinant Antibody (CL750-98012, Clone: 230353B7), or Isotype Control. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

• 

  FC experiment of human peripheral blood leukocytes using CL750-98012

  1x10^6 human peripheral blood leukocytes were surface stained with 5 ul CoraLite® Plus 750 Anti-Human CEACAM5/8 (CD66b/e) Rabbit Recombinant Antibody (CL750-98012, Clone: 230353B7) (red), or Isotype Control (blue). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: human peripheral blood leukocytes

Dilution recommandée

Application	Dilution
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Informations sur le produit

CL750-98012 cible CEACAM5/8 (CD66b/e) dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: carcinoembryonic antigen-related cell adhesion molecule 8
• Masse moléculaire calculée: 38 kDa
• Numéro d’acquisition GenBank: BC026263
• Symbole du gène: CEACAM8
• Identification du gène (NCBI): 1088
• Conjugaison: CoraLite® Plus 750 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 755 nm / 780 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide and 0.5% BSA
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) belong to the immunoglobulin superfamily of cell adhesion molecules. CEACAMs play major roles in cell-cell and cell-ECM adhesion and have been implicated in controlling cell proliferation, angiogenesis, and tissue remodeling (PMID: 23021083). Carcinoembryonic antigen (CEA), also known as CEACAM5 or CD66e mainly serves as a cell adhesion molecule mediating intercellular contact by both homophilic and heterophilic binding (PMID: 21731662). CEACAM8, also known as CD66b, CGM6 or NCA-95, is a glycosylphosphatidylinositol (GPI)-linked glycoprotein expressed on granulocytes and is involved in regulating adhesion and activation of eosinophils (PMID: 8104998; 18056392; 18056392). This antibody is raised against 35-319 aa of human CEACAM8/CD66b and can cross-react with CEACAM5/CD66e.

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