Anticorps Polyclonal de lapin anti-CFHR3

CFHR3 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 16583-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 16583-1-AP (same clone as 16583-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 16583-1-AP (CFHR3 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16583-1-PBS in a different storage buffer formulation.

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  WB analysis of human heart using 16583-1-AP (same clone as 16583-1-PBS)

  human heart tissue were subjected to SDS PAGE followed by western blot with 16583-1-AP (CFHR3 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16583-1-PBS in a different storage buffer formulation.

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  IP experiment of HepG2 using 16583-1-AP (same clone as 16583-1-PBS)

  IP result of anti-CFHR3 (IP:16583-1-AP, 4ug; Detection:16583-1-AP 1:300) with HepG2 cells lysate 2400ug. This data was developed using the same antibody clone with 16583-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver using 16583-1-AP (same clone as 16583-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 16583-1-AP (CFHR3 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 16583-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver using 16583-1-AP (same clone as 16583-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 16583-1-AP (CFHR3 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 16583-1-PBS in a different storage buffer formulation.

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Informations sur le produit

16583-1-PBS cible CFHR3 dans les applications de WB, IHC, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: CFHR3 Protéine recombinante Ag9963
• Nom complet: complement factor H-related 3
• Masse moléculaire calculée: 330 aa, 37 kDa
• Poids moléculaire observé: 45-56 kDa
• Numéro d’acquisition GenBank: BC058009
• Symbole du gène: CFHR3
• Identification du gène (NCBI): 10878
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CFHR3, also named as DOWN16, belongs to the complement factor H-related protein family. Expressed by the liver and secreted in plasma, human CFHR3 is composed of five short consensus repeats (SCRs), and it also has a 19-amino acid signal peptide and four N-linked glycosylation sites. It may be involved in complement regulation. Deletion of CFHR1 and CFHR3 genes was found to be associated with decreased risk of age-related macular degeneration (AMD), and with an increased risk of atypical hemolytic-uremic syndrome (aHUS).

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