Anticorps Polyclonal de lapin anti-Properdin/PFC

Properdin/PFC Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 17192-1-PBS

Synonymes

CFP, BFD, Complement factor P, complement factor properdin, PFC

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Galerie de données de validation

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  WB analysis of Jurkat using 17192-1-AP (same clone as 17192-1-PBS)

  Jurkat cells were subjected to SDS PAGE followed by western blot with 17192-1-AP (CFP Antibody) at dilution of 1:300 incubated at 4 degree celsius over night. This data was developed using the same antibody clone with 17192-1-PBS in a different storage buffer formulation.

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  IHC staining of human spleen using 17192-1-AP (same clone as 17192-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human spleen tissue slide using 17192-1-AP (CFP Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 17192-1-PBS in a different storage buffer formulation.

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  IHC staining of human spleen using 17192-1-AP (same clone as 17192-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human spleen tissue slide using 17192-1-AP (CFP Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 17192-1-PBS in a different storage buffer formulation.

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Informations sur le produit

17192-1-PBS cible Properdin/PFC dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Properdin/PFC Protéine recombinante Ag9798
• Nom complet: complement factor properdin
• Masse moléculaire calculée: 469 aa, 51 kDa
• Poids moléculaire observé: 50 kDa
• Numéro d’acquisition GenBank: BC015756
• Symbole du gène: CFP
• Identification du gène (NCBI): 5199
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CFP, also named as Properdin or PFC, is a 469 amino acid protein, which contains 7 TSP type-1 domains. CFP as secreted protein is a positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Properdin deficiency poses a significant risk for severe meningococcal infections (PMID: 22229731). Properdin may be novel biomarker for future risk of type 2 diabetes (PMID: 22338105).

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